Decode Biology. De-risk Development.
What is DECODE
DECODE transforms molecular data into decision-ready evidence for oncology drug development. By decoding latent patient biology, it helps teams optimize trial design, identify response-relevant populations, and de-risk assets from early clinical development through launch.
See the Biology
Underneath
Turn Trial Data Into Development Strategy
From hidden biology to clinical decision
From hidden biology to clinical decision
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
The Greenway, Block C,
112-114 St Stephen's Green,
Dublin 2, D02 TD28
Dublin, Ireland
Decode Biology. De-risk Development.
What is DECODE
DECODE transforms molecular data into decision-ready evidence for oncology drug development. By decoding latent patient biology, it helps teams optimize trial design, identify response-relevant populations, and de-risk assets from early clinical development through launch.
See the Biology
Underneath
Turn Trial Data Into Development Strategy
From hidden biology to clinical decision
From hidden biology to clinical decision
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
The Greenway, Block C,
112-114 St Stephen's Green,
Dublin 2, D02 TD28
Dublin, Ireland
Decode Biology. De-risk Development.
What is DECODE
DECODE transforms molecular data into decision-ready evidence for oncology drug development. By decoding latent patient biology, it helps teams optimize trial design, identify response-relevant populations, and de-risk assets from early clinical development through launch.
See the Biology
Underneath
Turn Trial Data Into Development Strategy
From hidden biology to clinical decision
From hidden biology to clinical decision
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
01
Latent Patient Space
Trial population mapped multi-omic data
DECODE integrates patient omics into a unified latent space to reveal hidden biological structure across the full trial population.
Date Inputs
Multi-Omic Profiles
Asset Details
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
02
Biology Clusters
Hidden molecular subtypes and patient states emerge
Patients are grouped by shared biological programs, not diagnosis alone. DECODE resolves molecular subtypes, disease states, and patient segments that may be associated with response or resistance.
Biology Signals
Molecular Subtypes
Patient States
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
03
Response & Resistance
Mechanistic signals explain who responds, who resists, and why
DECODE connects biological clusters to predicted treatment outcomes, helping generate testable hypotheses around mechanism of action, resistance biology, and responder enrichment.
Mechanistic Insights
Responder Biology
Resistance Drivers & Pathway Signals
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
04
Strategy
Biology-defined cohorts inform trial strategy
Validated responder-enriched populations can guide cohort selection, biomarker strategy, enrollment criteria, indication focus, and next-stage clinical development planning.
Development Strategy
Cohort Selection
Biomarker Strategy
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
What is DECODE?
DECODE is a clinical decision engine that transforms clinical trial, real-world evidence, and patient omics data into mechanistic insight for oncology development.
What problem does DECODE solve?
DECODE helps teams understand why patients respond, resist, or progress by decoding latent biology hidden within clinical and multi-omic data.
What data does DECODE use?
DECODE can integrate clinical trial data, patient outcomes, metadata, and multi-omic profiles to map biology across a trial population.
What is the final output of DECODE?
DECODE produces decision-ready evidence, including responder-enriched populations, mechanistic hypotheses, validation signals, and trial strategy recommendations.
Can DECODE be hosted privately?
Yes. DECODE can be deployed in a secure Nexomic-managed environment or within a private cloud or on-premise infrastructure, depending on data governance and security requirements.
The Greenway, Block C,
112-114 St Stephen's Green,
Dublin 2, D02 TD28
Dublin, Ireland