Nexomic and Alpha Clinical Partner to De-Risk Oncology Drug Development

Jul 29, 2026

Nexomic and Alpha Clinical Partner to De-Risk Oncology Drug Development

Collaboration will bring DECODE’s AI-powered multi-omic intelligence into oncology clinical development programmes to inform trial design, biomarker strategy, patient stratification and Go/No-Go decisions.

LONDON, July 17, 2026 – Nexomic today announced a partnership with Alpha Clinical Developments, a global full-service clinical research organisation, to integrate DECODE’s AI-powered multi-omic intelligence into oncology clinical development programmes.

The partnership combines Alpha Clinical Developments’ oncology clinical development and trial strategy expertise with Nexomic’s ability to decode the biology of treatment response and resistance.

A major challenge in oncology development is that patients with the same diagnosis can have fundamentally different tumor biology and treatment outcomes. These biological differences can obscure meaningful treatment effects and make it difficult to identify which patients are most likely to benefit.
Built on DeepOmic, Nexomic’s tumor-agnostic multi-omic AI foundation model, DECODE analyses clinical, real-world and multi-omic patient data to identify the biological drivers of response and resistance and define biologically relevant patient populations.

The resulting intelligence can inform trial design, biomarker strategy, patient stratification and enrichment, cohort definition and Go/No-Go decisions—helping sponsors make better development decisions earlier.

Alpha Clinical Developments supports sponsors across the oncology development lifecycle, combining clinical development strategy with protocol design, study delivery and regulatory planning. Integrating DECODE into these programs will enable development strategies to be informed not only by diagnosis and clinical characteristics, but also by the underlying biology that determines treatment response.
Many oncology programs fail not because the therapy has no effect, but because the trial cannot identify which patients are most likely to benefit,” said Mohammad Ghosheh, Co-Founder and CEO of Nexomic. “DECODE was built to address this challenge by decoding the biology of treatment response and resistance. Working with Alpha Clinical Developments allows us to bring this intelligence directly into oncology development strategy, where the most consequential decisions are made.

Better oncology development begins with a deeper understanding of the biology that determines treatment response,” said Prof. Humaid Al Shamsi, Co-Founder and Chairman of Nexomic. “This partnership brings DECODE’s multi-omic intelligence into clinical development programes, supporting stronger patient stratification, biomarker planning and critical programe decisions.

Our sponsors need more than well-executed trials; they need the right development decisions to be made early,” said Adnan Mahmood, CEO of Alpha Clinical Developments. “DECODE brings real-patient biology into the development process, helping sponsors better understand which patients a therapy may benefit and build stronger evidence behind their strategy.”
The collaboration will initially focus on applying DECODE within oncology clinical development programes, with the potential to expand across additional development questions and tumor types over time.

About Nexomic
Nexomic is a Dublin-based precision oncology TechBio company using frontier AI and patient multi-omic data to understand the biology behind treatment response and resistance. At its core is DeepOmic, a tumour-agnostic multi-omic AI foundation model trained on patient data from more than 30 countries. Built on this foundation, Nexomic develops solutions across the oncology lifecycle, including DISCOVER for therapeutic discovery and DECODE for de-risking oncology drug development and clinical trials.

About Alpha Clinical Developments
Alpha Clinical Developments is a global, full-service clinical research organisation supporting early- through late-phase clinical development, post-marketing and real-world studies. Since 2012, the company has supported sponsors worldwide across clinical consulting, pharmacovigilance, research and development operations, and clinical talent solutions.

7/29/26

Nexomic Team

Writing about AI, multi-omics, and the future of precision oncology at Nexomic.

Related

News

The Greenway, Block C,
112-114 St Stephen's Green, 


Dublin 2, D02 TD28


Dublin, Ireland

Nexomic and Alpha Clinical Partner to De-Risk Oncology Drug Development

Jul 29, 2026

Nexomic and Alpha Clinical Partner to De-Risk Oncology Drug Development

Collaboration will bring DECODE’s AI-powered multi-omic intelligence into oncology clinical development programmes to inform trial design, biomarker strategy, patient stratification and Go/No-Go decisions.

LONDON, July 17, 2026 – Nexomic today announced a partnership with Alpha Clinical Developments, a global full-service clinical research organisation, to integrate DECODE’s AI-powered multi-omic intelligence into oncology clinical development programmes.

The partnership combines Alpha Clinical Developments’ oncology clinical development and trial strategy expertise with Nexomic’s ability to decode the biology of treatment response and resistance.

A major challenge in oncology development is that patients with the same diagnosis can have fundamentally different tumor biology and treatment outcomes. These biological differences can obscure meaningful treatment effects and make it difficult to identify which patients are most likely to benefit.
Built on DeepOmic, Nexomic’s tumor-agnostic multi-omic AI foundation model, DECODE analyses clinical, real-world and multi-omic patient data to identify the biological drivers of response and resistance and define biologically relevant patient populations.

The resulting intelligence can inform trial design, biomarker strategy, patient stratification and enrichment, cohort definition and Go/No-Go decisions—helping sponsors make better development decisions earlier.

Alpha Clinical Developments supports sponsors across the oncology development lifecycle, combining clinical development strategy with protocol design, study delivery and regulatory planning. Integrating DECODE into these programs will enable development strategies to be informed not only by diagnosis and clinical characteristics, but also by the underlying biology that determines treatment response.
Many oncology programs fail not because the therapy has no effect, but because the trial cannot identify which patients are most likely to benefit,” said Mohammad Ghosheh, Co-Founder and CEO of Nexomic. “DECODE was built to address this challenge by decoding the biology of treatment response and resistance. Working with Alpha Clinical Developments allows us to bring this intelligence directly into oncology development strategy, where the most consequential decisions are made.

Better oncology development begins with a deeper understanding of the biology that determines treatment response,” said Prof. Humaid Al Shamsi, Co-Founder and Chairman of Nexomic. “This partnership brings DECODE’s multi-omic intelligence into clinical development programes, supporting stronger patient stratification, biomarker planning and critical programe decisions.

Our sponsors need more than well-executed trials; they need the right development decisions to be made early,” said Adnan Mahmood, CEO of Alpha Clinical Developments. “DECODE brings real-patient biology into the development process, helping sponsors better understand which patients a therapy may benefit and build stronger evidence behind their strategy.”
The collaboration will initially focus on applying DECODE within oncology clinical development programes, with the potential to expand across additional development questions and tumor types over time.

About Nexomic
Nexomic is a Dublin-based precision oncology TechBio company using frontier AI and patient multi-omic data to understand the biology behind treatment response and resistance. At its core is DeepOmic, a tumour-agnostic multi-omic AI foundation model trained on patient data from more than 30 countries. Built on this foundation, Nexomic develops solutions across the oncology lifecycle, including DISCOVER for therapeutic discovery and DECODE for de-risking oncology drug development and clinical trials.

About Alpha Clinical Developments
Alpha Clinical Developments is a global, full-service clinical research organisation supporting early- through late-phase clinical development, post-marketing and real-world studies. Since 2012, the company has supported sponsors worldwide across clinical consulting, pharmacovigilance, research and development operations, and clinical talent solutions.

7/29/26

Nexomic Team

Writing about AI, multi-omics, and the future of precision oncology at Nexomic.

Related

News

The Greenway, Block C,
112-114 St Stephen's Green, 


Dublin 2, D02 TD28


Dublin, Ireland

Nexomic and Alpha Clinical Partner to De-Risk Oncology Drug Development

Jul 29, 2026

Nexomic and Alpha Clinical Partner to De-Risk Oncology Drug Development

Collaboration will bring DECODE’s AI-powered multi-omic intelligence into oncology clinical development programmes to inform trial design, biomarker strategy, patient stratification and Go/No-Go decisions.

LONDON, July 17, 2026 – Nexomic today announced a partnership with Alpha Clinical Developments, a global full-service clinical research organisation, to integrate DECODE’s AI-powered multi-omic intelligence into oncology clinical development programmes.

The partnership combines Alpha Clinical Developments’ oncology clinical development and trial strategy expertise with Nexomic’s ability to decode the biology of treatment response and resistance.

A major challenge in oncology development is that patients with the same diagnosis can have fundamentally different tumor biology and treatment outcomes. These biological differences can obscure meaningful treatment effects and make it difficult to identify which patients are most likely to benefit.
Built on DeepOmic, Nexomic’s tumor-agnostic multi-omic AI foundation model, DECODE analyses clinical, real-world and multi-omic patient data to identify the biological drivers of response and resistance and define biologically relevant patient populations.

The resulting intelligence can inform trial design, biomarker strategy, patient stratification and enrichment, cohort definition and Go/No-Go decisions—helping sponsors make better development decisions earlier.

Alpha Clinical Developments supports sponsors across the oncology development lifecycle, combining clinical development strategy with protocol design, study delivery and regulatory planning. Integrating DECODE into these programs will enable development strategies to be informed not only by diagnosis and clinical characteristics, but also by the underlying biology that determines treatment response.
Many oncology programs fail not because the therapy has no effect, but because the trial cannot identify which patients are most likely to benefit,” said Mohammad Ghosheh, Co-Founder and CEO of Nexomic. “DECODE was built to address this challenge by decoding the biology of treatment response and resistance. Working with Alpha Clinical Developments allows us to bring this intelligence directly into oncology development strategy, where the most consequential decisions are made.

Better oncology development begins with a deeper understanding of the biology that determines treatment response,” said Prof. Humaid Al Shamsi, Co-Founder and Chairman of Nexomic. “This partnership brings DECODE’s multi-omic intelligence into clinical development programes, supporting stronger patient stratification, biomarker planning and critical programe decisions.

Our sponsors need more than well-executed trials; they need the right development decisions to be made early,” said Adnan Mahmood, CEO of Alpha Clinical Developments. “DECODE brings real-patient biology into the development process, helping sponsors better understand which patients a therapy may benefit and build stronger evidence behind their strategy.”
The collaboration will initially focus on applying DECODE within oncology clinical development programes, with the potential to expand across additional development questions and tumor types over time.

About Nexomic
Nexomic is a Dublin-based precision oncology TechBio company using frontier AI and patient multi-omic data to understand the biology behind treatment response and resistance. At its core is DeepOmic, a tumour-agnostic multi-omic AI foundation model trained on patient data from more than 30 countries. Built on this foundation, Nexomic develops solutions across the oncology lifecycle, including DISCOVER for therapeutic discovery and DECODE for de-risking oncology drug development and clinical trials.

About Alpha Clinical Developments
Alpha Clinical Developments is a global, full-service clinical research organisation supporting early- through late-phase clinical development, post-marketing and real-world studies. Since 2012, the company has supported sponsors worldwide across clinical consulting, pharmacovigilance, research and development operations, and clinical talent solutions.

7/29/26

Nexomic Team

Writing about AI, multi-omics, and the future of precision oncology at Nexomic.

Related

News

The Greenway, Block C,
112-114 St Stephen's Green, 


Dublin 2, D02 TD28


Dublin, Ireland